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Hallucinogen use in emergency care linked to higher bipolar disorder risk, study finds.
A Canadian study published December 2, 2025, finds people hospitalized or treated in emergency departments for hallucinogen use—like ketamine, LSD, or psilocybin—were six times more likely to receive mania treatment and four times more likely to be diagnosed with bipolar disorder within three years compared to those hospitalized for other reasons.
The research analyzed over 85,000 patient records from 2008 to 2022, noting most individuals had prior mental health or substance use issues.
While the findings suggest a link between acute hallucinogen use and future mood disorders, researchers caution the results apply mainly to those seeking urgent care and may not reflect broader user populations.
They stress the need for further study to understand risks, especially as hallucinogens are explored for therapeutic use.
El uso de alucinógenos en la atención de emergencia está relacionado con un mayor riesgo de trastorno bipolar, según un estudio.