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flag Women stopping GLP-1 drugs before or early in pregnancy gained more weight and faced higher pregnancy risks.

flag A new study of nearly 150,000 pregnancies found that women who stopped GLP-1 receptor agonist drugs before or early in pregnancy gained significantly more weight and faced higher risks of gestational diabetes, hypertension, and preterm birth compared to those not exposed. flag The retrospective analysis, covering 2016 to 2025, showed exposed women gained an average of 13.7 kg versus 10.5 kg in unexposed women, with no significant differences in cesarean delivery or baby size. flag Most exposed women had obesity or preexisting diabetes. flag The findings highlight the need for better guidance on managing these medications in reproductive-age women.

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