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flag Scientists developed a new bioreactor method to mass-produce lung organoids for personalized disease research and drug testing.

flag Scientists at the University of Duisburg-Essen, led by Professor Diana Klein, have created a scalable, automated method for producing lung organoids using a bioreactor, advancing personalized lung disease research. flag These lab-grown tissue models, derived from stem cells, mimic human lung structure better than traditional cultures and may enable high-throughput drug testing and individualized therapy prediction. flag While bioreactor-grown organoids differ slightly in cell composition—showing fewer alveolar spheres—they offer a more efficient, less labor-intensive alternative to manual methods and reduce reliance on animal testing. flag The technique, published in Frontiers in Bioengineering and Biotechnology, holds promise for improving cancer treatment outcomes through personalized testing, though further optimization of bioreactor design and growth conditions is needed.

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