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A clinical trial found metformin reduces insulin needs by 12% in type 1 diabetes patients without improving insulin resistance.
A new Australian clinical trial found that metformin, a common diabetes drug, reduces insulin needs by about 12% in people with type 1 diabetes, despite not improving insulin resistance.
The six-month study, involving 40 adults with long-term type 1 diabetes, used precise metabolic testing and found no significant change in insulin sensitivity, but a meaningful decrease in insulin dosage.
Researchers say this could ease the physical and emotional burden of daily insulin use, offering a potential low-cost addition to treatment.
The findings, published in Nature Communications, suggest metformin may help improve quality of life, though further research is needed to understand the mechanism.
Un ensayo clínico encontró que la metformina reduce las necesidades de insulina en un 12% en pacientes con diabetes tipo 1 sin mejorar la resistencia a la insulina.