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flag Johns Hopkins researchers found an AI model using chest CT scans can detect chronic stress via adrenal gland size, offering a non-invasive, accurate way to predict heart risks.

flag Researchers at Johns Hopkins University have developed an AI model that identifies chronic stress using routine chest CT scans by measuring adrenal gland volume, a biomarker linked to long-term stress. flag The Adrenal Volume Index (AVI), derived from existing imaging data, correlates with stress questionnaires, cortisol levels, allostatic load, and higher risks of heart failure and mortality. flag Unlike single cortisol tests, AVI reflects cumulative physiological stress. flag Validated over up to 10 years, the biomarker independently predicts cardiovascular outcomes and could enable widespread, non-invasive screening without additional radiation or testing, offering a major step toward objective stress assessment in clinical care.

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