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Blocking EYA and PLK1 proteins kills aggressive, resistant cancers in lab studies.
Australian researchers have found that blocking two proteins, EYA and PLK1, simultaneously kills aggressive, treatment-resistant cancers like neuroblastoma and glioblastoma through a synthetic lethal effect.
The study, published in Genes & Development, shows cancer cells depend on both proteins to survive, making their combined inhibition a promising new therapy path.
The discovery could lead to targeted treatments for hard-to-treat tumors.
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El bloqueo de las proteínas EYA y PLK1 mata cánceres agresivos y resistentes en estudios de laboratorio.