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flag A man with a gene for early Alzheimer’s has avoided the disease for 25 years, offering scientists clues for prevention.

flag A man in his 60s has remained free of Alzheimer’s for 25 years despite carrying the PSEN1 E280A genetic mutation, which typically causes early-onset Alzheimer’s in the 40s or 50s. flag His exceptional resistance is prompting scientists to study his brain and lifestyle for clues that could lead to new prevention strategies. flag With nearly 7 million Americans currently living with Alzheimer’s and projections of 14 million by 2060, this rare case offers hope for breakthroughs in understanding and combating the disease.

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