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An Australian blood test using immune markers predicts ovarian cancer patients' response to PARP inhibitors more accurately than DNA tests.
A new blood test developed by Australian researchers can better predict which ovarian cancer patients will respond to PARP inhibitor drugs by measuring immune biomarkers related to immune cell activity in tumors.
Unlike current DNA-based tests, this non-invasive approach reflects real-time cancer biology and showed improved accuracy, especially in patients previously classified as non-responders.
The test, validated in a clinical trial of 114 women, could help avoid ineffective treatments, reduce side effects, and guide more personalized care.
While further validation is needed, experts view it as a promising step toward precision medicine in ovarian cancer.
Un análisis de sangre australiano que utiliza marcadores inmunológicos predice la respuesta de los pacientes con cáncer de ovario a los inhibidores de PARP con mayor precisión que las pruebas de ADN.