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Trinity College Dublin's nasal whooping cough vaccine, AIBP, shows strong protection in trials and may prevent spread.
Researchers at Trinity College Dublin have developed a nasal vaccine, AIBP, using inactivated whooping cough bacteria that shows strong protection in preclinical trials by preventing both infection and transmission.
Unlike current injectable vaccines, it triggers localized immune responses in the respiratory tract, blocking bacterial colonization in the nose and lungs.
The needle-free approach may offer longer-lasting immunity and could be adapted for other respiratory diseases.
Funded by Irish and EU sources, the vaccine is advancing toward human trials, with potential to significantly reduce community spread of whooping cough and other pathogens.
La vacuna nasal contra la tos ferina de Trinity College Dublin, AIBP, muestra una fuerte protección en ensayos y puede prevenir la propagación.