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Japanese researchers used AI to find new cancer targets in the "dark genome," advancing personalized vaccine development for tough-to-treat cancers.
Researchers from Japan’s JFCR and NEC used AI to analyze whole-genome data from breast cancer and soft tissue sarcoma, identifying previously unknown cancer-specific antigens in the "dark genome," offering new targets for personalized vaccines.
The findings, presented at the SITC 2025 meeting, could expand treatment options for hard-to-treat cancers with low conventional neoantigen levels.
The work supports Japan’s push for precision medicine through genomic and AI-driven therapies.
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Investigadores japoneses utilizaron la IA para encontrar nuevos objetivos de cáncer en el "genoma oscuro", avanzando en el desarrollo de vacunas personalizadas para cánceres difíciles de tratar.