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Scientists are using modified bacteria to target tumors, deliver treatments, and self-destruct, showing promise in trials for tough cancers.
Scientists are engineering bacteria like Listeria and Salmonella to target solid tumors, deliver cancer therapies, and self-destruct afterward, minimizing harm to healthy tissue.
These "living medicines" exploit the tumor’s low oxygen and weak immune environment, showing promise in phase 2 trials when combined with immunotherapies or chemotherapy for hard-to-treat cancers like pancreatic and cervical.
Over 70 clinical trials and 500 studies have explored this approach, with ongoing efforts to enhance safety, control bacterial behavior, and prevent unintended effects.
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Los científicos están utilizando bacterias modificadas para atacar tumores, administrar tratamientos y autodestruirse, mostrando promesa en ensayos para cánceres difíciles.