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T cell therapy targeting HPV cured advanced cancers in patients, with some remaining cancer-free for years.
A landmark study by Rutgers Cancer Institute and RWJBarnabas Health, supported by the National Cancer Institute, reveals that T cell therapies targeting HPV antigens led to sustained complete remissions in patients with HPV-related cancers, including head and neck, cervical, and anal cancers.
Announced on November 7, 2025, the clinical trial found that some patients remained cancer-free for several years after treatment, even following prior standard therapies.
The results suggest engineered T cells can effectively re-engage the immune system to control cancer long-term, marking a significant advance in immunotherapy for virus-driven malignancies.
La terapia con células T dirigida contra el VPH curó cánceres avanzados en pacientes, y algunos permanecieron libres de cáncer durante años.