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Neurogastrx's NG101 drug reduced nausea and vomiting in semaglutide users by up to 70% in a Phase 2 trial.
Neurogastrx reported positive Phase 2 trial results for NG101, an oral drug that significantly reduced nausea and vomiting in people taking semaglutide, a common GLP-1 medication for obesity and diabetes.
In a study of 90 adults, NG101 cut nausea by 40%, vomiting by 67%, and reduced symptom severity by 70% compared to placebo, with fewer side effects.
The drug, which targets nausea without affecting the brain’s appetite control center, may help patients stay on effective treatments longer.
Results were presented at ObesityWeek 2025, and the company also named a new CEO as it advances development.
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El fármaco NG101 de Neurogastrx redujo las náuseas y los vómitos en usuarios de semaglutida hasta en un 70% en un ensayo de fase 2.