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Prenatal COVID-19 exposure linked to higher neurodevelopmental disorder risk in children, especially boys and third-trimester infections.
A large Massachusetts study of over 18,000 births from March 2020 to May 2021 found that children exposed to COVID-19 in the womb had a 29% higher odds of neurodevelopmental disorders like speech or motor delays by age three, with the highest risk in boys and when infection occurred in the third trimester.
Most mothers were unvaccinated, and the study used universal testing to identify infections.
While the overall risk remains low, researchers suggest maternal inflammation from severe infection may disrupt fetal brain development, particularly during rapid brain growth in the third trimester.
The study does not prove causation, and experts note that current risks may be lower due to immunity and variants.
La exposición prenatal al COVID-19 está relacionada con un mayor riesgo de trastornos del desarrollo neurológico en los niños, especialmente en los niños y las infecciones del tercer trimestre.