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flag Opioid deaths rose 12% in the U.S. last year, driven by fentanyl, especially in rural Midwest and Southern states.

flag A new federal report released on November 5, 2025, reveals a 12% increase in opioid-related deaths across the U.S. over the past year, with synthetic opioids like fentanyl now involved in over 70% of overdose fatalities. flag The data, collected by the Centers for Disease Control and Prevention, highlights rising fatalities in rural Midwest and Southern states, prompting calls for expanded access to naloxone and addiction treatment programs. flag Public health officials warn that current prevention efforts are insufficient to counter the growing crisis.

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