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flag A nationwide oxycodone-acetaminophen shortage, caused by manufacturing issues, will persist into early 2026, with limited availability expected to gradually improve.

flag A shortage of oxycodone-acetaminophen painkillers like Percocet is expected to continue into early 2026 due to ongoing manufacturing issues, according to Canadian pharmacists and Health Canada. flag While Tylenol 3 has largely returned to shelves, supplies of Tylenol 2 and 4 remain limited. flag Some oxycodone-acetaminophen availability may resume in December, but backorders will constrain supply. flag Health officials recommend alternative pain medications, with gradual improvement expected by the new year.

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