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Long-term use of common drugs like antibiotics and benzodiazepines can permanently alter gut bacteria, a new study finds.
A new study of 2,509 Estonian adults finds that common prescription drugs—including antibiotics, antidepressants, PPIs, benzodiazepines, and beta-blockers—can alter the gut microbiome in ways that last years after stopping use.
Researchers linked long-term medication use to persistent changes in microbial diversity, with effects worsening with duration and multiple drugs.
Benzodiazepines, especially alprazolam, showed strong negative impacts.
The findings suggest past drug use should be considered in health assessments and microbiome research, highlighting the need to balance treatment benefits with long-term gut health.
El uso a largo plazo de medicamentos comunes como antibióticos y benzodiazepinas puede alterar permanentemente las bacterias intestinales, según un nuevo estudio.