The Lions lost 30-17 to the Chiefs, ending a four-game win streak amid key errors and a postgame brawl.

The Detroit Lions lost 30-17 to the Kansas City Chiefs at Arrowhead Stadium on October 12, 2025, ending a four-game winning streak. The Chiefs, led by Patrick Mahomes, dominated offensively and defensively, capitalizing on key mistakes, including a critical fourth-down drop by All-Pro wide receiver Amon-Ra St. Brown and a penalty that nullified a touchdown. A postgame scuffle erupted when Lions safety Brian Branch punched Chiefs wide receiver JuJu Smith-Schuster, prompting condemnation from Lions coach Dan Campbell and potential disciplinary action. The loss exposed the Lions’ struggles when trailing and highlighted defensive lapses, especially in the second half.