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Early menopause linked to higher dementia risk; HRT may help, but more research is needed.
A new study linking early menopause to higher dementia risk and hormone replacement therapy (HRT) to potential protection has been published in the Journal of Alzheimer’s Disease.
Analyzing data from 1,329 women in the Framingham Heart Study, researchers found that longer lifetime exposure to estrogen—through later menopause, higher estrogen levels, or more children—was associated with better cognitive function and larger brain volumes.
While HRT may lower dementia risk, researchers stress the need for further study and caution against drawing definitive conclusions.
The findings highlight sex-related differences in dementia, as women make up nearly two-thirds of Alzheimer’s cases.
La menopausia temprana está vinculada a un mayor riesgo de demencia; la TRH puede ayudar, pero se necesita más investigación.