The 49ers play the Buccaneers on Sunday, October 11, 2025, at 1 PM ET on FOX.

The San Francisco 49ers will face the Tampa Bay Buccaneers on Sunday, October 11, 2025, in a regular-season NFL matchup. The game will be televised on FOX, with kickoff scheduled for 1:00 PM ET. Fans can stream the game live through the FOX Sports app or website, as well as through supported streaming services like Hulu + Live TV, YouTube TV, and Sling TV. Additional details on broadcast teams and regional availability may vary.