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flag Dexamethasone boosts TB treatment by enhancing immune cell function and reducing inflammation, but experts urge caution due to side effects.

flag A new study in Scientific Reports finds that dexamethasone, a steroid, can enhance tuberculosis treatment by boosting macrophages' ability to kill Mycobacterium tuberculosis, improve cell survival, and reduce bacterial load through improved autophagy and phagosomal acidification. flag It also balances immune response by lowering both pro- and anti-inflammatory cytokines and reducing glycolysis, limiting harmful inflammation without weakening defense. flag The findings support reconsidering targeted steroid use alongside antibiotics, especially in inflammatory TB cases, though experts caution against overuse due to side effects and stress the need for careful protocols and further research.

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