U.S. stock futures edged up Friday as major stocks fell, led by Nurix Therapeutics, Venture Global, and Orthopediatrics.

U.S. stock futures rose slightly Friday, but several major stocks fell in pre-market trading. Nurix Therapeutics dropped 5.8% after reporting a larger-than-expected Q3 loss and weak sales. Venture Global plunged 18.4% following an arbitration resolution, while Orthopediatrics slid 15% after lowering its 2025 revenue forecast. Inventiva, USANA Health Sciences, Nanobiotix, Diginex, and Levi Strauss also declined, with Levi Strauss falling despite beating earnings and sales estimates.