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flag Colts host injured Cardinals, with Murray possibly out and Gannon fined.

flag The Indianapolis Colts, 4-1 and averaging 32.6 points per game, host the Arizona Cardinals, who may be without starting quarterback Kyler Murray due to a foot injury. flag Daniel Jones, in his first season with Indianapolis, is playing at a career-high level, posting a 71.3% completion rate and 105.1 passer rating, leading the team to 163 points in five games—the most in franchise history through that span since 2007. flag Backup Jacoby Brissett, a former Colts starter, is preparing to take over if Murray cannot play. flag The Cardinals also face a coaching scandal after head coach Jonathan Gannon was fined $100,000 for punching a player, and several key players, including Darius Robinson, are injured. flag The Colts have six players on their injury report, including starter Kenny Moore II, who is out with an Achilles issue.

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