Buccaneers and Seahawks, both 3-1, face key injuries ahead of Week 5 clash.

The Tampa Bay Buccaneers and Seattle Seahawks entered their Week 5 matchup on October 5, 2025, with multiple key players inactive due to injuries. The Buccaneers sat out Mike Evans, Bucky Irving, Jamel Dean, Christian Izien, and Benjamin Morrison, while the Seahawks missed DeMarcus Lawrence, Julian Love, Devon Witherspoon, and Josh Jones. Despite the absences, rookie Nick Emmanwori returned from an ankle injury and Connor O’Toole made his debut, with three quarterbacks on Seattle’s roster. Both teams, entering as 3-1 first-place contenders, faced significant challenges in their secondary and backfield, forcing strategic adjustments ahead of the 4:25 p.m. ET game at Lumen Field.