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AI at McMaster University rapidly discovered enterololin, a promising antibiotic targeting harmful gut bacteria while sparing beneficial ones, potentially offering safer treatment for Crohn’s and similar conditions.
A McMaster University researcher, Jon Stokes, used AI to identify a potential new antibiotic, enterololin, that targets harmful gut bacteria like E. coli without damaging beneficial microbes, offering hope for treating Crohn’s disease and other inflammatory bowel conditions.
The AI predicted effective chemical structures and mechanisms in under two minutes, cutting discovery time from years to months and costs from millions to $60,000.
Human-led validation over six months confirmed the results, highlighting the need for expert oversight.
With Canada’s IBD patient numbers projected to rise from 320,000 to nearly 470,000, the breakthrough represents a major step toward safer, more targeted treatments, though human trials are still needed.
La IA en la Universidad McMaster descubrió rápidamente la enterololina, un antibiótico prometedor dirigido a las bacterias intestinales dañinas mientras ahorra las beneficiosas, ofreciendo potencialmente un tratamiento más seguro para la enfermedad de Crohn y condiciones similares.