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Poor sleep linked to brain aging in UK study, with each sleep score drop adding six months to brain age.
A large study of 27,500 UK Biobank participants links poor sleep to accelerated brain aging, with those scoring low on sleep quality measures having brains that appear, on average, one year older than their actual age.
Using MRI scans and machine learning, researchers found that each one-point drop in sleep score correlated with a six-month increase in the brain-age gap.
Low-grade inflammation explained over 10% of this link, suggesting it may be a key mechanism.
The findings, published in eBioMedicine on October 1, 2025, indicate that improving sleep could help slow brain aging and reduce cognitive decline risk, though self-reported data and the generally healthy participant pool limit broad applicability.
El sueño deficiente vinculado al envejecimiento del cerebro en un estudio del Reino Unido, con cada caída en la puntuación de sueño añadiendo seis meses a la edad del cerebro.