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flag Over 25 million codeine prescriptions were issued in England in 2024, with NHS warnings on dependence and side effects.

flag In 2024, over 25 million Schedule 5 controlled drugs, including codeine, were prescribed in England, with codeine used for moderate to severe pain when other medications fail. flag Available by prescription or over the counter in combination with paracetamol or ibuprofen, it can cause side effects like constipation, nausea, dizziness, and fatigue in more than 1% of users, especially with prolonged use. flag The NHS warns of dependence risk and recommends short-term use, proper dosing, and increased dietary fibre to manage constipation.

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