Trump to impose $100K fee on new H-1B visas starting Sept. 21, 2025, affecting major sponsors like Mayo Clinic.

President Donald Trump announced a $100,000 one-time fee on certain new H-1B visa petitions filed on or after September 21, 2025, affecting major sponsors like Mayo Clinic and the University of Minnesota. The fee, significantly higher than the usual $3,380, applies only to new petitions, not existing holders or renewals. Mayo Clinic, the third-largest H-1B sponsor in Minnesota, had 366 approvals in 2025, including 153 for clinical residents. While physicians may be exempted if deemed in the national interest, specifics remain unclear. Legal challenges are expected over the fee’s authority. Both institutions affirm their commitment to international recruitment, but the policy’s impact on healthcare staffing and research remains uncertain.