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flag Regeneron's stock dropped 46% year-to-date in 2025 after mixed COPD trial results raised pipeline concerns.

flag Regeneron Pharmaceuticals' stock fell in the second quarter of 2025, declining 2.89% in September and 46.36% over the past year, closing at $563.90 on September 26. flag The drop followed mixed results from a key COPD trial for its drug itepekimab, with only one of two trials meeting expectations. flag Despite broader market recovery from tariff-related losses, investor concerns grew over pipeline uncertainty and clinical outcomes, contributing to underperformance, particularly for major holders like the Baird Chautauqua International and Global Growth Fund.

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