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A new blood test detected tumor cells and vesicles in most glioblastoma patients, offering a promising non-invasive monitoring tool.
A new study presented at the 7th Advances in Circulating Tumour Cells meeting shows ANGLE’s Parsortix® system detected circulating tumour cells (CTCs) in 60% of newly diagnosed glioblastoma patients, with CTC clusters found in 78% of positive cases.
All CTCs showed a mesenchymal phenotype, a trait often missed by standard methods.
Extracellular vesicles were detected in 73% of patients, supporting liquid biopsy potential.
The technology enables simultaneous isolation of CTCs and EVs from a single blood draw, offering a minimally invasive way to monitor tumour biology and treatment response—especially valuable since ctDNA is rarely detected in glioma due to the blood-brain barrier.
The research is for non-diagnostic use and requires further validation.
Un nuevo análisis de sangre detectó células tumorales y vesículas en la mayoría de los pacientes con glioblastoma, ofreciendo una prometedora herramienta de monitoreo no invasivo.