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flag Rochester, MN physicians earn the highest average salaries in the U.S., at $495,532, led by the Mayo Clinic.

flag Physicians in Rochester, Minnesota, earn the highest average salaries in the U.S., with an average annual income of $495,532, according to the Doximity 2025 compensation analysis, adjusted for cost of living. flag The city leads nationally in physician pay and salary growth, rising at 8.7% annually, fueled by the presence of the Mayo Clinic and other top-tier medical institutions. flag Minneapolis also ranks highly, with an average physician salary of $452,598, placing eighth nationally. flag Minnesota’s strong healthcare infrastructure and large physician workforce contribute to its high standing. flag The report highlights broader trends in physician compensation across major U.S. cities, with Rochester standing out for both pay and growth.

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