The Los Angeles Chargers beat the Denver Broncos 23-20 on September 21, 2025, to start 3-0 for the first time since 2002.

The Los Angeles Chargers defeated the Denver Broncos 23-20 on September 21, 2025, securing their first 3-0 start since 2002. Justin Herbert led a late-game drive, throwing a 20-yard touchdown to Keenan Allen with 2:44 remaining, then guided the Chargers to a game-winning 43-yard field goal by Cameron Dicker. Herbert finished 28 of 47 for 300 yards and one interception, becoming the youngest NFL player to reach 2,000 career completions. The Chargers improved to 3-0, beating all three AFC West opponents in their first three games. Denver, despite a 17-10 lead, failed to hold off the comeback, committing 10 penalties and converting only 2 of 13 third downs. Rookie Omarion Hampton had a touchdown and 70 rushing yards, while Bo Nix finished 14 of 23 for 153 yards with a touchdown and an interception. Injuries included Najee Harris with an Achilles injury and guard Mekhi Becton with a concussion.