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Duke study finds pancreatic alpha cells boost GLP-1 during stress, offering natural blood sugar control for type 2 diabetes.
A Duke University study finds that pancreatic alpha cells may naturally produce more bioactive GLP-1 than previously believed, especially during metabolic stress, offering a potential internal mechanism to improve blood sugar control in type 2 diabetes.
Unlike earlier assumptions, these cells appear to switch from glucagon to GLP-1 production, with GLP-1 proving a stronger stimulator of insulin release.
Using advanced detection methods, researchers confirmed active GLP-1 levels, suggesting alpha cells act as a built-in backup system.
This discovery could lead to new therapies that enhance the body’s own GLP-1 production, reducing reliance on external drugs.
El estudio de Duke encuentra que las células alfa pancreáticas aumentan GLP-1 durante el estrés, ofreciendo control natural de azúcar en la sangre para la diabetes tipo 2.