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flag Charlie Sheen said Matthew Perry was not sober while promoting his ketamine recovery memoir, and expressed regret before Perry’s 2023 death from acute ketamine effects.

flag In a 2025 interview, Charlie Sheen said he believed Matthew Perry was not sober when promoting his 2022 memoir detailing his ketamine addiction and recovery. flag Sheen, who has his own history with substance abuse, expressed regret for not reaching out to Perry before his death in October 2023 from acute ketamine effects. flag Perry’s book described his struggles with anxiety and depression, and a toxicology report confirmed ketamine as the cause of death. flag In August 2024, five people were charged in connection with Perry’s death, including Jasveen Sangha, who pleaded guilty to federal charges related to supplying the fatal ketamine dose; the others are scheduled for sentencing in late 2025.

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