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A study finds genetic variants linked to better metabolic health in obese people, helping identify subtypes and predict complications.
A new study led by Mount Sinai and the University of Copenhagen, published in Nature Medicine on September 15, 2025, identifies genetic variants linked to healthier metabolic profiles despite high body fat, explaining why some obese individuals avoid conditions like diabetes and heart disease.
Analyzing data from over 450,000 people of European ancestry, researchers found 205 genome regions associated with obesity but better metabolic health, enabling the creation of a genetic risk score to classify obesity subtypes.
This could help doctors predict complications and develop personalized treatments, though future research will focus on diverse populations.
Un estudio encuentra variantes genéticas vinculadas a una mejor salud metabólica en personas obesas, lo que ayuda a identificar subtipos y predecir complicaciones.