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flag SF 49ers face uncertain Week 2 outlook as QB Brock Purdy and TE George Kittle are injured.

The San Francisco 49ers face uncertainty for Week 2 with quarterback Brock Purdy injured in their Week 1 win. Purdy's availability depends on his toe and shoulder injuries, with the toe considered worse. Star tight end George Kittle will miss multiple weeks due to a hamstring injury. If Purdy can't play, Mac Jones will start. The team signed Kendrick Bourne to bolster their receiver depth.

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