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flag Scientists find a protein that makes bone cancers resist immunotherapy, offering new treatment hopes.

flag Researchers have identified a protein, DKK1, produced by bone metastases that reprograms immune cells, making cancers in bones resistant to immunotherapy. flag This discovery suggests that blocking DKK1 could improve immunotherapy's effectiveness against bone tumors, which currently have limited treatment options. flag Additionally, CHI3L3 may serve as a biomarker to tailor treatments for patients with high immune resistance.

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