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Researchers find that boosting sialic acid in insulin-producing cells may prevent type 1 diabetes.
Mayo Clinic researchers have discovered that a sugar molecule, sialic acid, which helps cancer cells evade the immune system, can also protect insulin-producing beta cells in type 1 diabetes.
By engineering these cells to produce more sialic acid, they were 90% effective in preventing diabetes in preclinical models.
This method could lead to new treatments that protect beta cells without broad immune suppression.
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Los investigadores han descubierto que aumentar el ácido sialico en las células productoras de insulina puede prevenir la diabetes tipo 1.