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flag Colorectal cancer deaths among Americans under 50 have surged, outpacing other cancers in this age group.

flag Early-onset gastrointestinal cancers, particularly colorectal cancer, are rising globally, especially in high-income countries, and now lead in cancer deaths for Americans under 50. flag Risk factors include obesity, a Western diet, non-alcoholic fatty liver disease, smoking, and alcohol. flag Despite more aggressive treatments, younger patients often face worse outcomes and quality of life. flag Researchers call for better screening and prevention strategies.

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