Steelers select Derrick Harmon, a defensive tackle from Oregon, 21st overall, bypassing QB Sanders.

The Pittsburgh Steelers selected Oregon defensive tackle Derrick Harmon with the 21st pick in the 2025 NFL Draft, passing on quarterback Shedeur Sanders. Harmon, a 6-foot-5, 310-pound player, was second-team All-American last season, recording five sacks and 10.5 tackles for loss. The Steelers chose Harmon to bolster their defense after a tough playoff loss to the Baltimore Ravens. Harmon described the draft moment as "bittersweet" as his mother is in the hospital on life support.