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flag Scientists identify protein key to fat loss in advanced cancer, suggesting new treatments.

flag Chinese scientists have found that a protein called macrophage migration inhibitory factor (MIF) is key to irreversible fat loss in advanced cancer patients with cachexia. flag This condition, which causes significant weight loss and muscle wasting and accounts for 20% of cancer deaths, is exacerbated by MIF triggering chronic inflammation in fat tissue. flag The researchers discovered that blocking MIF could alleviate these symptoms in mice, potentially leading to new treatments to improve quality of life and survival for cancer patients.

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