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Researchers find mechanism helping pancreatic cancer evade immune system, suggesting new treatment paths.
Researchers from Taiwan identified a new mechanism, TIMP1-CD63, which helps pancreatic cancer cells evade the immune system and grow.
This mechanism, along with a DUSP2 gene deficiency, protects about 90% of KRAS-mutated cancer cells, accelerating cancer progression.
The study, published in Molecular Cancer, suggests that disrupting this cycle could lead to new treatments for pancreatic cancer, a disease with a survival rate under 10%.
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Los investigadores encuentran un mecanismo que ayuda a que el cáncer de páncreas evada el sistema inmunitario, sugiriendo nuevas vías de tratamiento.