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Researchers develop new PET imaging probe to detect inflammation, aiming for human trials.
Researchers at Dana-Farber Cancer Institute have developed a new PET imaging probe, CD45-PET, to detect inflammation by targeting CD45, a marker on immune cells.
The probe has shown potential in animal models, correlating well with clinical symptoms and tissue analysis.
A human version of the probe has also been developed and tested successfully in humanized mouse models.
The team is now aiming for clinical trials, with the goal of using CD45-PET to guide anti-inflammatory treatments and diagnose inflammatory conditions.
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Los investigadores desarrollan una nueva sonda de imagen PET para detectar la inflamación, con el objetivo de ensayos humanos.