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Study reveals CAR T cells with different signaling types offer varying benefits in cancer treatment.
A recent study in Science Advances reveals how different types of CAR T cells, used in cancer immunotherapy, target and destroy cancer cells.
Researchers found that CAR T cells with CD28.ζ signaling kill cancer cells quickly, while those with 4-1BB.ζ signaling maintain long-term cancer cell elimination.
This discovery could help in developing CAR T therapies for a wider range of cancers, including challenging solid tumors.
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El estudio revela que las células CAR T con diferentes tipos de señalización ofrecen beneficios variables en el tratamiento del cáncer.