Novartis' gene therapy shows promise in improving motor functions for children with SMA Type 2.

Novartis' Phase III STEER study showed positive results for intrathecal onasemnogene abeparvovec (OAV101 IT) in treating children and young adults with SMA Type 2, marking a first for gene therapy in this group. The study found improved motor function scores and a favorable safety profile, with common side effects including upper respiratory infections and vomiting. Novartis aims to share these findings with regulatory agencies in 2025 to make the treatment available.

December 30, 2024
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