Tamoxifen cuts breast cancer recurrence by nearly half in some DCIS patients, study shows.

Recent research at the San Antonio Breast Cancer Symposium suggests that tamoxifen can significantly reduce the recurrence of breast cancer in patients with "good-risk" ductal carcinoma in situ (DCIS) who opt for breast-conserving surgery without radiotherapy. "Good-risk" refers to tumors that are grade 1 or 2, 2.5 cm or smaller, and have clear surgical margins of 3 mm or more. The study showed a 15-year recurrence rate of 11.4% for tamoxifen-treated patients compared to 19% for those not treated with tamoxifen. Another study indicates that active monitoring could be a safe alternative to immediate surgery for low-risk DCIS, with similar outcomes for invasive cancer rates over two years. However, more long-term studies are needed.

4 months ago
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