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Penn researchers find ketogenic diet may boost CAR T cell cancer therapy effectiveness; trial ongoing.
Researchers at the University of Pennsylvania found that a ketogenic diet could enhance CAR T cell therapy effectiveness by increasing beta-hydroxybutyrate (BHB), which boosts CAR T cells' ability to fight cancer.
A Phase I clinical trial is underway to assess the safety and efficacy of combining BHB supplementation with CAR T cell therapy.
This could offer a cost-effective and low-toxicity approach to improving cancer treatment outcomes.
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Los investigadores de Penn encuentran que la dieta cetogénica puede aumentar la eficacia de la terapia del cáncer de células CAR T; ensayo en curso.