Rookie Isaac Guerendo steps up as the San Francisco 49ers' starting running back against the Chicago Bears.

Isaac Guerendo, a rookie running back for the San Francisco 49ers, is set to make his NFL starting debut against the Chicago Bears, filling in for injured stars Christian McCaffrey and Jordan Mason. Guerendo, known for his adaptability and solid performance, has averaged 5.9 yards per carry this season. The 49ers also have backup Patrick Taylor Jr. and newly claimed Israel Abanikanda to support their running game.