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flag Scientists find brain circuit in females that controls mating acceptance based on reproductive state.

flag Scientists at the Champalimaud Foundation discovered a neural circuit in the brain's ventromedial hypothalamus (VMH) that controls whether female mammals accept or reject mating attempts. flag This circuit, sensitive to progesterone, influences defensive behaviors like kicking during non-receptive phases, while reducing activity during fertile periods to allow mating. flag The findings, published in Neuron, reveal a dual-neuron system that regulates sexual behavior based on reproductive state.

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