Scientists find brain circuit in females that controls mating acceptance based on reproductive state.

Scientists at the Champalimaud Foundation discovered a neural circuit in the brain's ventromedial hypothalamus (VMH) that controls whether female mammals accept or reject mating attempts. This circuit, sensitive to progesterone, influences defensive behaviors like kicking during non-receptive phases, while reducing activity during fertile periods to allow mating. The findings, published in Neuron, reveal a dual-neuron system that regulates sexual behavior based on reproductive state.

November 25, 2024
5 Articles