Merck's new PAH drug, Winrevair, shows promise but raises concerns over high cost and bleeding risks.

Merck's drug, Winrevair, has shown significant benefits for patients with pulmonary arterial hypertension (PAH), a condition causing high blood pressure in the lungs. In a late-stage study, it was found to reduce the risk of disease worsening, lung transplantation, or death. Approved in the US and other countries, Winrevair is the first treatment targeting a specific protein called activin. Despite its effectiveness, the drug, priced at about $238,000 annually, has raised concerns over potential bleeding risks.

November 25, 2024
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